?????????? ??? ???????????? / ?????? ?????????? ???????, ??????????? ??????????, ?????? ??????? ???????? / ??????????? ????????? ???????? ??????? ??????? ??????????? ????????

Дата: 2007-10-25 20:04

????. 4
?????????? ???????????? TIMI 11B
????? ?????????? ???????? ??????? ????????? ???????? ????? ?
8 ???? ??? 14,5% 0,048
(OR 0.83)
??????????? 12,4%
43 ???? ??? 19,7% 0,048
(OR 0.85)
??????????? 17,3%
Circulation. 1999;100:1593-1601
??????????:
OR: odds ratio
?????? ? ?????? ???????????? ???????? ???????? ?????????? ??????? ???????????? ?? ????????? ? ??????? ? ???????????? ???? ???????????? (2,9% vs 1,5%; ?=0,021), ? ?????? ???? ?? ??????? ???????????? ?????? ?? ??????????? ????? ?????.
E.M. Antman et al. ????????? ????-?????? ????????????? ???????????? ? ????????? ? ??????? ????????? ?? ?????? ???????????? ESSENCE ? TIMI 11B (n=7081). ??? ????????? ?????????? ?????? ?????????????????? ????????????????? ???????? ????? ????????? ???????? ????? ????? ??? ?? 20% ? ?????? ???????????? (??. ????.5).
???? 5.
?????? ????-??????? ???????????? ESSENCE ? TIMI 11B.
?????????? ????? OR P
8 ???? 21% 0,71 0,02
14 ???? 21% 0,79 0,0005
43 ???? 20% 0,80 0,0006
Circulation. 1999;100:1602-1608
??????????:
OR: odds ratio
????????? ?? ??????????? ?? ?????? ????????? ?????? ????????????????? ????????????? ??????????? ???????????? ????????????????? ????????? FRAX.I.S. (Comparison of two treatment durations (6 days and 14 days) of a low molecular weight heparin with a 6-day treatment of unfractionated heparin in the initial management of unstable angina or non-Q wave myocardial infarction: FRAX.I.S.) ????????? ? ????? ????????? ???? ??????????????? ????????? ?????????? ?????????????????? ???????? ??????????? ? ???????? ???????????????????? ???????? ??? ??????? ??????? ???????????? ???????????? ? ????????? ???????? ??? ????? Q. ????? ??????????????? 3468 ????????? ? ??????? ?????? 48 ????? ???????? ???????????. ??????? ?????? ???????? ???????? ??? ????????? ? ???????????? ??????????? ??????? ???????? ??????? ? ???? 5000 ??, ????? ????? ??????????? ??????? ? ??????? 6±2 ???? ? ???????????? ???? ? ???????? 1,5-2,5 ?? ????????. ?????? ??????????? ???? ????????? ?? ??? ?????????: ? ????? ?? ??? ??? ???????????? ??????????? ???????? ????? ??????????? ? ???? 86 ??/??, ? ????? ?????????? ????????????? ???????? ?????? ? ????? ????? ? ???? 86 ??/?? ? ??????? 6±2 ????. ? ?????? ????????? ????? ? ?????? ???????????? ??????????? ???????? ????? ??????????? ? ???? 86 ??/??, ?????? ??????????? ????????? ???????? ??????????? ? ???? 86 ??/?? ?????? ? ????? ???????????? 14 ????. ? ????? ??????? ???????? ???????? ??????? ? ???? 100-325 ??.
??? ??????? ??????? ????????? ???????? ????? ??????????? ??????????? ??????????? ????? ??????? ????????? ?? ??????? ??????? ??? ????? 6, ??? ? ????? 14 ???? ??????? (??. ???? 6).
??????? 6.
?????????? ???????????? FRAX.I.S.
?????? ?????? ??????????, ??? ??????? ????????? ???????? ?????1 ?
??? 6 14,9% ?????????? 6 vs ???
0,85
14 18,1%
?????????? 6 6 13,8%
14 17,8% ?????????? 14 vs ???
0,24
?????????? 14 6 15,8%
14 20,0%
Eur Heart J 1999 Nov;20(21):1553-62

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